PifferPilfer

PifferPilfer

Vindicated by Ancient DNA, Forgotten by Academia: The Bittersweet Fate of My Polygenic Score Research

New preprint provides empirical validation for predicting complex traits in ancient populations

Davide Piffer's avatar
Davide Piffer
Jul 19, 2025
∙ Paid

A new preprint by Cox et al. offers compelling evidence supporting the use of polygenic scores (PGS) to study complex traits in ancient populations. By directly comparing PGS predictions with skeletal measurements from 568 ancient Eurasians (38,000–600 BP), this work addresses critical questions about PGS reliability – with significant implications for …

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